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Definition: Citrulline is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a byproduct of the reaction catalyzed by NOS family (NOS; EC 184.108.40.206). It is made from arginine by the enzyme trichohyalin at the inner root sheath and medulla of hair follicles. Arginine is first oxidized into N-hydroxyl-arginine, which is then further oxidized to citrulline concomitant with release of nitric oxide
Application: Unlike some amino acids, L-citrulline isn't used to make protein, but it might help increase other chemicals the body needs to make protein. It might also help improve blood flow and reduce blood pressure. People use L-citrulline for athletic performance such as muscle building, boosting endurance and recovery, sickle cell disease, erectile dysfunction (ED), high blood pressure in the lungs, heart disease, and many other conditions
Form: L-Citrulline is in white crystalline powder, with no less than 98.0%
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